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Axin is a cytosolic scaffold for core Wnt signaling components, including Dvl, APC, casein kinase 1α (CK1α), GSK-3, and β-catenin. The Axin complex serves two, seemingly opposing functions in the Wnt pathway. Recruitment of the Axin complex to LRP5/6 is essential for pathway activation, yet, in the absence of Wnts, the complex inhibits the ...
Axin. Axin is a cytosolic scaffold for core Wnt signaling components, including Dvl, APC, casein kinase 1α (CK1α), GSK-3, and β-catenin. The Axin complex serves two, seemingly opposing functions in the Wnt pathway. Recruitment of the Axin complex to LRP5/6 is essential for pathway activation, yet, in the absence of Wnts, the complex inhibits ...
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Axienomics (AXIN) is currently ranked as the #12869 cryptocurrency by market cap. Today it reached a high of $0.000000, and now sits at $0.000000. Axienomics (AXIN) price is up 0.210000% in the last 24 hours. Axienomics is currently trading on 1 exchange, with a 24hr trade volume of $184.
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AXIN Price Live Data. The live Axienomics price today is $2.58e-8 USD with a 24-hour trading volume of $435.82 USD.. We update our AXIN to USD price in real-time. Axienomics is down 1.43% in the last 24 hours. The current CoinMarketCap ranking is #7459, with a live market cap of not available.
AXIN1 (Axin 1) is a Protein Coding gene. Diseases associated with AXIN1 include Hepatocellular Carcinoma and Caudal Duplication Anomaly.Among its related pathways are Misspliced GSK3beta mutants stabilize beta-catenin and EphB-EphrinB Signaling.Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and protein kinase binding.
Axin-1 is a protein that in humans is encoded by the AXIN1 gene. Function. This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin (cadherin ...
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Function. The Axin-related protein, Axin2, presumably plays an important role in the regulation of the stability of beta-catenin in the Wnt signaling pathway, like its rodent homologs, mouse conductin/rat axil.In mouse, conductin organizes a multiprotein complex of APC (adenomatous polyposis of the colon), beta-catenin, glycogen synthase kinase 3-beta, and conductin, which leads to the ...
Axin is the product of the mouse fused locus. Mutations in this gene result in axial duplications in mouse embryos. Ectopic expression of wild type axin in dorsal blastomeres of Xenopus embryos causes ventralization (Zeng et al 1997). Axin associates directly with β-catenin, GSK-3 β and APC and is implicated in down- regulating Wnt signaling (Ikeda, 1998; Sakanaka, 1998; Ikeda, 1998; Itoh ...
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